ReactionDirections

namespace: SMRUCC.genomics.Assembly.MetaCyc.Schema.Metabolism

This slot specifies the directionality of a reaction. This slot is used in slightly different
ways in class Reactions and Enzymatic-Reactions. In class Enzymatic-Reactions, the slot specifies
information about the direction of the reaction associated with the enzymatic-reaction, by the
associated enzyme. That is, the directionality information refers only to the case in which the
reaction is catalyzed by that enzyme, and may be influenced by the regulation of that enzyme.

The slot is particularly important to fill for reactions that are not part of a pathway, because
for such reactions, the direction cannot be determined automatically, whereas for reactions
within a pathway, the direction can be inferred from the pathway context. This slot aids the
user and software in inferring the direction in which the reaction typically occurs in
physiological settings, relative to the direction in which the reaction is stored in the database.

Properties

IrreversibleLeftToRight

For all practical purposes, the reaction occurs only in the specified direction in
physiological settings, because of chemical properties of the reaction.

IrreversibleRightToLeft

For all practical purposes, the reaction occurs only in the specified direction in
physiological settings, because of chemical properties of the reaction.

LeftToRight

The reaction occurs in the specified direction in physiological settings, but it is unknown
whether the reaction is considered irreversible.

PhysiolLeftToRight

The reaction occurs in the specified direction in physiological settings, because of several
possible factors including the energetics of the reaction, local concentrations of reactants
and products, and the regulation of the enzyme or its expression.

PhysiolRightToLeft

The reaction occurs in the specified direction in physiological settings, because of several
possible factors including the energetics of the reaction, local concentrations of reactants
and products, and the regulation of the enzyme or its expression.

Reversible

The reaction occurs in both directions in physiological settings.

RightToLeft

The reaction occurs in the specified direction in physiological settings, but it is unknown
whether the reaction is considered irreversible.